‘Uncovering bone formation processes for the design of regenerative therapies’
RESEARCH
Scope of the lab
Bone is a complex organ capable of self-repair! By studying how they form and heal, we aim at understanding their regenerative properties for clinical applications.
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AIM 1
In Vivo
Models
By in vivo development of human Bone organ/ossicles, we set-up an ideal model to study the formation of skeletal and hematopoietic tissues in a humanized set-up.
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AIM 2
In Vitro Models
Standard 2D culture do not reflect the complexity of living tissues/organs. We develop 3D systems providing advanced Bone Organ models of higher biological fidelity.
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AIM 3
Design of grafts
We target the development of cell-based but cell-free grafts. By customizing their growth-factors content, we expect to efficiently instruct tissue regeneration.
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