Principal investigator:

Paul Bourgine

‘Uncovering bone formation processes for the design of regenerative therapies’

News

11-26-2019
10-25-2019
08-01-2019
RESEARCH

Scope of the lab

Bone is a complex organ capable of self-repair! By studying how they form and heal, we aim at understanding their regenerative properties for clinical applications.

AIM 1

In Vivo
Models

By in vivo development of human Bone organ/ossicles, we set-up an ideal model to study the formation of skeletal and hematopoietic tissues in a humanized set-up.

AIM 2

In Vitro Models

Standard 2D culture do not reflect the complexity of living tissues/organs. We develop 3D systems providing advanced Bone Organ models of higher biological fidelity.

AIM 3

Design of grafts

We target the development of cell-based but cell-free grafts. By customizing their growth-factors content, we expect to efficiently instruct tissue regeneration.